Lab members
Lab members
Embedded Files
Kozo Yoneda
Kozo Yoneda
Visiting Scientist
Visiting Scientist
Ph.D., Chemistry, University of Tsukuba, Japan
Ph.D., Chemistry, University of Tsukuba, Japan
M.S., Chemistry, University of Tsukuba, Japan
M.S., Chemistry, University of Tsukuba, Japan
B.S., Chemistry, University of Tsukuba, Japan
B.S., Chemistry, University of Tsukuba, Japan
email: kozoo “@” umich.edu
email: kozoo “@” umich.edu
Research interests: engineering antibody drug conjugates, bispecific antibodies, and developability platforms for drug-like biologic therapeutic candidates.
Research interests: engineering antibody drug conjugates, bispecific antibodies, and developability platforms for drug-like biologic therapeutic candidates.
Bivek Chaulagain
Bivek Chaulagain
Postdoctoral Fellow
Postdoctoral Fellow
Ph.D., North Dakota State University
Ph.D., North Dakota State University
M.PHARM., Dr. Hari Singh Gour Vishwavidyalaya, India
M.PHARM., Dr. Hari Singh Gour Vishwavidyalaya, India
B.PHARM., Rajiv Gandhi University of Health Science, India
B.PHARM., Rajiv Gandhi University of Health Science, India
email: bivekc “@” umich.edu
email: bivekc “@” umich.edu
Research interests: neurodegenerative disease, antibody therapeutics, bispecific antibodies, CNS delivery.
Research interests: neurodegenerative disease, antibody therapeutics, bispecific antibodies, CNS delivery.
Alicia Dubinski
Alicia Dubinski
Postdoctoral Fellow
Postdoctoral Fellow
Ph.D., Neuroscience, University of Montreal (CHUM), Canada
Ph.D., Neuroscience, University of Montreal (CHUM), Canada
M.S., Molecular Genetics, University of Waterloo, Canada
M.S., Molecular Genetics, University of Waterloo, Canada
B.S., Honours Biochemistry, University of Waterloo, Canada
B.S., Honours Biochemistry, University of Waterloo, Canada
email: dualicia “@” umich.edu
email: dualicia “@” umich.edu
Research interests: ALS mechanisms, TDP-43 pathology, excitotoxicity, CNS drug delivery and imaging, and neurodegenerative disease progression.
Research interests: ALS mechanisms, TDP-43 pathology, excitotoxicity, CNS drug delivery and imaging, and neurodegenerative disease progression.
Yun-Huai (Wade) Kuo
Yun-Huai (Wade) Kuo
Doctoral Student (Chemical Engineering)
Doctoral Student (Chemical Engineering)
University of Michigan (2021-current)
University of Michigan (2021-current)
B.S., Chemical and Biomolecular Engineering, Johns Hopkins University
B.S., Chemical and Biomolecular Engineering, Johns Hopkins University
email: ywadekuo “@” umich.edu
email: ywadekuo “@” umich.edu
Research interests: Antibody engineering, antibody-drug conjugates, bispecific antibodies for brain delivery of neuroprotective antibodies.
Research interests: Antibody engineering, antibody-drug conjugates, bispecific antibodies for brain delivery of neuroprotective antibodies.
Yunxuan Xie
Yunxuan Xie
Doctoral Student (Pharmaceutical Sciences)
Doctoral Student (Pharmaceutical Sciences)
University of Michigan (2021-current)
University of Michigan (2021-current)
M.S.E., Chemical & Biomolecular Engineering, Johns Hopkins University
M.S.E., Chemical & Biomolecular Engineering, Johns Hopkins University
B.E., Pharmaceutical Engineering, Hubei University of Chinese Medicine
B.E., Pharmaceutical Engineering, Hubei University of Chinese Medicine
email: yunxuan “@” umich.edu
email: yunxuan “@” umich.edu
Research interests: Antibody engineering, drug delivery, blood-brain barrier, bispecific antibody shuttles, antibody-drug conjugates.
Research interests: Antibody engineering, drug delivery, blood-brain barrier, bispecific antibody shuttles, antibody-drug conjugates.
Cecilia Spesia
Cecilia Spesia
Doctoral Student (Pharmaceutical Sciences)
Doctoral Student (Pharmaceutical Sciences)
University of Michigan (2021-current)
University of Michigan (2021-current)
B.S., Biochemistry, Villanova University
B.S., Biochemistry, Villanova University
email: cspesia “@” umich.edu
email: cspesia “@” umich.edu
Research interests: Drug delivery, bispecific antibody shuttles, blood-brain barrier, bispecific antibodies for brain delivery.
Research interests: Drug delivery, bispecific antibody shuttles, blood-brain barrier, bispecific antibodies for brain delivery.
Namir Khalasawi
Namir Khalasawi
Doctoral Student (Pharmaceutical Sciences)
Doctoral Student (Pharmaceutical Sciences)
NIH F31 Fellow (2026-current)
NIH F31 Fellow (2026-current)
University of Michigan (2021-current)
University of Michigan (2021-current)
B.S., Chemical and Biomolecular Engineering, Johns Hopkins University
B.S., Chemical and Biomolecular Engineering, Johns Hopkins University
email: namirk “@” umich.edu
email: namirk “@” umich.edu
Research interests: Immunoengineering, agonist antibodies, antibody-drug conjugates, cancer therapeutics, brain delivery of biologics and antibody-drug conjugates.
Research interests: Immunoengineering, agonist antibodies, antibody-drug conjugates, cancer therapeutics, brain delivery of biologics and antibody-drug conjugates.
Omar Abed
Omar Abed
Doctoral Student (Chemical Engineering), co-advised with Drs. James Moon and Colin Greineder
Doctoral Student (Chemical Engineering), co-advised with Drs. James Moon and Colin Greineder
University of Michigan (2021-current)
University of Michigan (2021-current)
B.S., Chemical Engineering, Arizona State University
B.S., Chemical Engineering, Arizona State University
email: oabed “@” umich.edu
email: oabed “@” umich.edu
Research interests: inflammatory disorders, neuroinflammation, immunoengineering, cytokine engineering.
Research interests: inflammatory disorders, neuroinflammation, immunoengineering, cytokine engineering.
Ece Akin
Ece Akin
Doctoral Student (Chemical Engineering)
Doctoral Student (Chemical Engineering)
University of Michigan (2022-current)
University of Michigan (2022-current)
B.S., Chemical Engineering, Boğaziçi University
B.S., Chemical Engineering, Boğaziçi University
email: eceakin “@” umich.edu
email: eceakin “@” umich.edu
Research interests: directed evolution, machine learning, antibody multiobjective optimization, brain drug delivery, bispecific antibodies, nanobodies, VHHs.
Research interests: directed evolution, machine learning, antibody multiobjective optimization, brain drug delivery, bispecific antibodies, nanobodies, VHHs.
Chloe Brown
Chloe Brown
Doctoral Student (Chemical Engineering)
Doctoral Student (Chemical Engineering)
University of Michigan (2023-current)
University of Michigan (2023-current)
MChE, Chemical Engineering, Carnegie Mellon University
MChE, Chemical Engineering, Carnegie Mellon University
B.S., Chemical Engineering, Carnegie Mellon University
B.S., Chemical Engineering, Carnegie Mellon University
email: chloebr “@” umich.edu
email: chloebr “@” umich.edu
Research interests: protein computational design and analysis, protein language models, machine learning and artificial intelligence, antibody engineering and optimization.
Research interests: protein computational design and analysis, protein language models, machine learning and artificial intelligence, antibody engineering and optimization.
Yu-Hui (Eva) Huang
Yu-Hui (Eva) Huang
Doctoral Student (Chemical Engineering)
Doctoral Student (Chemical Engineering)
University of Michigan (2023-current)
University of Michigan (2023-current)
M.S., Chemical Engineering, University of California, Berkeley
M.S., Chemical Engineering, University of California, Berkeley
B.S., Chemical Engineering, National Taiwan University
B.S., Chemical Engineering, National Taiwan University
email: evahuang “@” umich.edu
email: evahuang “@” umich.edu
Research interests: antibody therapeutics, antibody engineering, developability analysis, high-throughput screening, machine learning.
Research interests: antibody therapeutics, antibody engineering, developability analysis, high-throughput screening, machine learning.
Dat Le Quoc Doi
Dat Le Quoc Doi
Doctoral Student (Chemical Engineering)
Doctoral Student (Chemical Engineering)
University of Michigan (2023-current)
University of Michigan (2023-current)
B.S., Chemical Engineering, New Mexico State University
B.S., Chemical Engineering, New Mexico State University
email: ddoi “@” umich.edu
email: ddoi “@” umich.edu
Research interests: bispecific antibodies, brain drug delivery, directed evolution, antibody engineering, machine learning.
Research interests: bispecific antibodies, brain drug delivery, directed evolution, antibody engineering, machine learning.
Juan Jiménez Mejía
Juan Jiménez Mejía
Doctoral Student (Chemical Engineering), co-advised with Dr. Greg Thurber
Doctoral Student (Chemical Engineering), co-advised with Dr. Greg Thurber
University of Michigan (2023-current)
University of Michigan (2023-current)
B.S., Chemical Engineering, University of Florida
B.S., Chemical Engineering, University of Florida
email: juanjim “@” umich.edu
email: juanjim “@” umich.edu
Research interests: brain drug delivery, antibody therapeutics, pharmacokinetic modeling, cancer.
Research interests: brain drug delivery, antibody therapeutics, pharmacokinetic modeling, cancer.
Deepika Tripu
Deepika Tripu
Doctoral Student (Chemical Biology), co-advised with Dr. Colin Greineder
Doctoral Student (Chemical Biology), co-advised with Dr. Colin Greineder
NIH T32 Fellow (2024-2026)
NIH T32 Fellow (2024-2026)
University of Michigan (2023-current)
University of Michigan (2023-current)
B.S., Biochemistry, University of Maryland, College Park
B.S., Biochemistry, University of Maryland, College Park
email: dtripu “@” umich.edu
email: dtripu “@” umich.edu
Research interests: CNS drug delivery, agonist antibodies, pharmacokinetics, neuroprotection, traumatic brain injury.
Research interests: CNS drug delivery, agonist antibodies, pharmacokinetics, neuroprotection, traumatic brain injury.
Dana Allababidi
Dana Allababidi
Doctoral Student (Chemical Engineering)
Doctoral Student (Chemical Engineering)
University of Michigan (2024-current)
University of Michigan (2024-current)
B.S., Chemical Engineering, University of Rhode Island
B.S., Chemical Engineering, University of Rhode Island
email: dallabab “@” umich.edu
email: dallabab “@” umich.edu
Research interests: brain drug delivery, antibody therapeutics, antibody-nucleic acid conjugates, antisense oligonucleotides.
Research interests: brain drug delivery, antibody therapeutics, antibody-nucleic acid conjugates, antisense oligonucleotides.
Hannah Wolfgang
Hannah Wolfgang
Doctoral Student (Chemical Engineering), co-advised with Dr. Thurber
Doctoral Student (Chemical Engineering), co-advised with Dr. Thurber
NIH T32 Fellow (2025-2027)
NIH T32 Fellow (2025-2027)
University of Michigan (2024-current)
University of Michigan (2024-current)
B.S., Chemical Engineering, Worcester Polytechnic Institute
B.S., Chemical Engineering, Worcester Polytechnic Institute
email: hewolf “@” umich.edu
email: hewolf “@” umich.edu
Research interests: brain drug delivery, antibody therapeutics, antibody-nucleic acid conjugates, antisense oligonucleotides, immunocytokines.
Research interests: brain drug delivery, antibody therapeutics, antibody-nucleic acid conjugates, antisense oligonucleotides, immunocytokines.
Jett Stad
Jett Stad
Doctoral Student (Pharmaceutical Sciences)
Doctoral Student (Pharmaceutical Sciences)
University of Michigan (2024-current)
University of Michigan (2024-current)
B.S., Biomedical Engineering, Purdue University
B.S., Biomedical Engineering, Purdue University
email: jstad “@” umich.edu
email: jstad “@” umich.edu
Research interests: directed evolution, protein engineering, bispecific antibodies, blood-brain barrier, CNS drug delivery, therapeutics, commercialization.
Research interests: directed evolution, protein engineering, bispecific antibodies, blood-brain barrier, CNS drug delivery, therapeutics, commercialization.
Hongru Zheng
Hongru Zheng
Doctoral Student (Pharmaceutical Sciences)
Doctoral Student (Pharmaceutical Sciences)
University of Michigan (2024-current)
University of Michigan (2024-current)
M.S., Pharmaceutics, Peking University
M.S., Pharmaceutics, Peking University
B.S., Pharmaceutical Sciences, Peking University
B.S., Pharmaceutical Sciences, Peking University
email: zhenghr “@” umich.edu
email: zhenghr “@” umich.edu
Research interests: CNS drug delivery, bispecific antibodies, blood-brain barrier, nucleic acid therapeutics, antisense oligonucleotides, neurodegenerative disease.
Research interests: CNS drug delivery, bispecific antibodies, blood-brain barrier, nucleic acid therapeutics, antisense oligonucleotides, neurodegenerative disease.
Jack Pezzillo
Jack Pezzillo
Doctoral Student (Chemical Engineering)
Doctoral Student (Chemical Engineering)
University of Michigan (2025-current)
University of Michigan (2025-current)
B.S., Chemical Engineering, University of Pittsburgh
B.S., Chemical Engineering, University of Pittsburgh
email: michpezz “@” umich.edu
email: michpezz “@” umich.edu
Research interests: neuroimmunology, neuroinflammation, CNS drug delivery, regulatory T cells, neurodegenerative disease.
Research interests: neuroimmunology, neuroinflammation, CNS drug delivery, regulatory T cells, neurodegenerative disease.
Kartik Kher
Kartik Kher
Doctoral Student (Chemical Engineering)
Doctoral Student (Chemical Engineering)
NSF Graduate Research Fellow (2026-2029)
NSF Graduate Research Fellow (2026-2029)
University of Michigan (2025-current)
University of Michigan (2025-current)
B.S., Chemical Engineering, University of Texas at Austin
B.S., Chemical Engineering, University of Texas at Austin
email: kartikkh “@” umich.edu
email: kartikkh “@” umich.edu
Research interests: therapeutic antibodies, CNS drug delivery, antibody engineering.
Research interests: therapeutic antibodies, CNS drug delivery, antibody engineering.
Kai Rubach
Kai Rubach
Doctoral Student (Pharmaceutical Sciences)
Doctoral Student (Pharmaceutical Sciences)
University of Michigan (2025-current)
University of Michigan (2025-current)
B.S., Chemistry, University of Florida
B.S., Chemistry, University of Florida
email: krubach “@” umich.edu
email: krubach “@” umich.edu
Research interests: immunoengineering, CNS drug delivery, antibody engineering.
Research interests: immunoengineering, CNS drug delivery, antibody engineering.
Hyun Jin Lee
Hyun Jin Lee
Doctoral Student (Pharmaceutical Sciences)
Doctoral Student (Pharmaceutical Sciences)
University of Michigan (2025-current)
University of Michigan (2025-current)
M.Sc., Biological Engineering, Ajou University, Suwon, Rep. of Korea
M.Sc., Biological Engineering, Ajou University, Suwon, Rep. of Korea
B.Sc., Chemical Engineering, Ajou University, Suwon, Rep. of Korea
B.Sc., Chemical Engineering, Ajou University, Suwon, Rep. of Korea
email: hjinlee “@” umich.edu
email: hjinlee “@” umich.edu
Research interests: antibody engineering, CNS drug delivery, nucleic acid therapeutics.
Research interests: antibody engineering, CNS drug delivery, nucleic acid therapeutics.
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