Lab members
Lab members
Michael (Mike) Lucas
Michael (Mike) Lucas
NIH F32 Postdoctoral Fellow
NIH F32 Postdoctoral Fellow
Ph.D. Chemical Engineering, University of Texas at Austin
Ph.D. Chemical Engineering, University of Texas at Austin
M.S. Chemical Engineering, University of Texas at Austin
M.S. Chemical Engineering, University of Texas at Austin
B.S., Chemical Engineering, University of Notre Dame
B.S., Chemical Engineering, University of Notre Dame
email: miclucas “@” umich.edu
email: miclucas “@” umich.edu
Research interests: Conformational antibodies, neurodegenerative disease, targeted drug delivery, directed evolution, protein engineering
Research interests: Conformational antibodies, neurodegenerative disease, targeted drug delivery, directed evolution, protein engineering
Na-Young Kwon
Na-Young Kwon
Postdoctoral Fellow
Postdoctoral Fellow
Ph.D., Chemistry, Korea Advanced Institute of Science and Technology (KAIST)
Ph.D., Chemistry, Korea Advanced Institute of Science and Technology (KAIST)
B.S., Chemistry, Korea Advanced Institute of Science and Technology (KAIST)
B.S., Chemistry, Korea Advanced Institute of Science and Technology (KAIST)
email: kwonn “@” umich.edu
email: kwonn “@” umich.edu
Research interests: Structural biology, biophysics, antibody engineering, antibody drug development
Research interests: Structural biology, biophysics, antibody engineering, antibody drug development
Murat Karadag
Murat Karadag
Postdoctoral Fellow
Postdoctoral Fellow
Ph.D., Molecular Biology and Genetics, Dokuz Eylul University Izmir International Biomedicine and Genome Institute, Turkey
Ph.D., Molecular Biology and Genetics, Dokuz Eylul University Izmir International Biomedicine and Genome Institute, Turkey
M.S., Biochemistry, Ege University, Turkey
M.S., Biochemistry, Ege University, Turkey
B.S., Biochemistry, Ege University, Turkey
B.S., Biochemistry, Ege University, Turkey
email: muratkar “@” umich.edu
email: muratkar “@” umich.edu
Research interests: antibody engineering and developability analysis, protein stability, aggregation-resistant antibodies, directed evolution, cancer imaging and therapeutics
Research interests: antibody engineering and developability analysis, protein stability, aggregation-resistant antibodies, directed evolution, cancer imaging and therapeutics
Wen-Hao Wu
Wen-Hao Wu
Postdoctoral Fellow
Postdoctoral Fellow
Ph.D., Chemistry and Molecular Engineering, Peking University, China
Ph.D., Chemistry and Molecular Engineering, Peking University, China
B.S., Chemistry, Renmin University of China
B.S., Chemistry, Renmin University of China
email: wenhaow “@” umich.edu
email: wenhaow “@” umich.edu
Research interests: antibody engineering, directed evolution, machine learning, brain drug delivery, bispecific antibodies
Research interests: antibody engineering, directed evolution, machine learning, brain drug delivery, bispecific antibodies
Hye Jin Lee
Hye Jin Lee
Postdoctoral Fellow
Postdoctoral Fellow
Ph.D., Pharmaceutical Sciences, University of Wisconsin, Madison
Ph.D., Pharmaceutical Sciences, University of Wisconsin, Madison
Pharm.D., College of Pharmacy, Korea University, South Korea
Pharm.D., College of Pharmacy, Korea University, South Korea
email: leehye “@” umich.edu
email: leehye “@” umich.edu
Research interests: antibody-drug conjugates, brain drug delivery, precision gene silencing, therapeutics
Research interests: antibody-drug conjugates, brain drug delivery, precision gene silencing, therapeutics
Neelan Sivaneri
Neelan Sivaneri
Doctoral Student (Chemical Engineering)
Doctoral Student (Chemical Engineering)
University of Michigan (2020-current)
University of Michigan (2020-current)
B.S., Chemical Engineering, Rutgers
B.S., Chemical Engineering, Rutgers
email: neelans “@” umich.edu
email: neelans “@” umich.edu
Research interests: antibody engineering, directed evolution, antibody brain targeting, co-optimization of antibody affinity and specificity
Research interests: antibody engineering, directed evolution, antibody brain targeting, co-optimization of antibody affinity and specificity
Tiexin Wang
Tiexin Wang
Doctoral Student (Chemical Engineering)
Doctoral Student (Chemical Engineering)
University of Michigan (2020-current)
University of Michigan (2020-current)
M.S., Chemical & Biomolecular Engineering, Johns Hopkins University
M.S., Chemical & Biomolecular Engineering, Johns Hopkins University
B.S., Pharmaceutical Engineering, Tianjin Univerisity
B.S., Pharmaceutical Engineering, Tianjin Univerisity
email: txwang “@” umich.edu
email: txwang “@” umich.edu
Research interests: cancer therapeutics, antibody-drug conjugates, protein engineering
Research interests: cancer therapeutics, antibody-drug conjugates, protein engineering
Hsin-Ting (Dennis) Chen
Hsin-Ting (Dennis) Chen
Doctoral Student (Chemical Engineering)
Doctoral Student (Chemical Engineering)
University of Michigan (2020-current)
University of Michigan (2020-current)
B.S., Chemical Engineering, National Tsing Hua University, Taiwan
B.S., Chemical Engineering, National Tsing Hua University, Taiwan
email: htdennis “@” umich.edu
email: htdennis “@” umich.edu
Research interests: machine learning, computational modeling, prediction of antibody affinity and specificity, antibody engineering
Research interests: machine learning, computational modeling, prediction of antibody affinity and specificity, antibody engineering
Layne Bond
Layne Bond
Doctoral Student (Chemical Biology), co-advised by Dr. Colin Greineder
Doctoral Student (Chemical Biology), co-advised by Dr. Colin Greineder
University of Michigan (2020-current)
University of Michigan (2020-current)
M.S., Chemical Biology of Cancer, University of Michigan
M.S., Chemical Biology of Cancer, University of Michigan
B.S., Neuroscience, University of Michigan
B.S., Neuroscience, University of Michigan
email: lgbond “@” umich.edu
email: lgbond “@” umich.edu
Research interests: neuroscience, targeted drug delivery, neurodegeneration, therapeutic antibodies, blood brain barrier
Research interests: neuroscience, targeted drug delivery, neurodegeneration, therapeutic antibodies, blood brain barrier
Yun-Huai (Wade) Kuo
Yun-Huai (Wade) Kuo
Doctoral Student (Chemical Engineering)
Doctoral Student (Chemical Engineering)
University of Michigan (2021-current)
University of Michigan (2021-current)
B.S., Chemical and Biomolecular Engineering, Johns Hopkins University
B.S., Chemical and Biomolecular Engineering, Johns Hopkins University
email: ywadekuo “@” umich.edu
email: ywadekuo “@” umich.edu
Research interests: Antibody engineering, antibody-drug conjugates, bispecific antibodies for brain delivery of neuroprotective antibodies
Research interests: Antibody engineering, antibody-drug conjugates, bispecific antibodies for brain delivery of neuroprotective antibodies
Yunxuan Xie
Yunxuan Xie
Doctoral Student (Pharmaceutical Sciences)
Doctoral Student (Pharmaceutical Sciences)
University of Michigan (2021-current)
University of Michigan (2021-current)
M.S.E., Chemical & Biomolecular Engineering, Johns Hopkins University
M.S.E., Chemical & Biomolecular Engineering, Johns Hopkins University
B.E., Pharmaceutical Engineering, Hubei University of Chinese Medicine
B.E., Pharmaceutical Engineering, Hubei University of Chinese Medicine
email: yunxuan “@” umich.edu
email: yunxuan “@” umich.edu
Research interests: Antibody engineering, drug delivery, blood-brain barrier, bispecific antibody shuttles, antibody-drug conjugates
Research interests: Antibody engineering, drug delivery, blood-brain barrier, bispecific antibody shuttles, antibody-drug conjugates
Cecilia Spesia
Cecilia Spesia
Doctoral Student (Pharmaceutical Sciences)
Doctoral Student (Pharmaceutical Sciences)
University of Michigan (2021-current)
University of Michigan (2021-current)
B.S., Biochemistry, Villanova University
B.S., Biochemistry, Villanova University
email: cspesia “@” umich.edu
email: cspesia “@” umich.edu
Research interests: Drug delivery, bispecific antibody shuttles, blood-brain barrier, bispecific antibodies for brain delivery
Research interests: Drug delivery, bispecific antibody shuttles, blood-brain barrier, bispecific antibodies for brain delivery
Namir Khalasawi
Namir Khalasawi
Doctoral Student (Pharmaceutical Sciences)
Doctoral Student (Pharmaceutical Sciences)
University of Michigan (2021-current)
University of Michigan (2021-current)
B.S., Chemical and Biomolecular Engineering, Johns Hopkins University
B.S., Chemical and Biomolecular Engineering, Johns Hopkins University
email: namirk “@” umich.edu
email: namirk “@” umich.edu
Research interests: Immunoengineering, agonist antibodies, antibody-drug conjugates, cancer therapeutics, brain delivery of biologics and antibody-drug conjugates
Research interests: Immunoengineering, agonist antibodies, antibody-drug conjugates, cancer therapeutics, brain delivery of biologics and antibody-drug conjugates
Ece Akin
Ece Akin
Doctoral Student (Chemical Engineering)
Doctoral Student (Chemical Engineering)
University of Michigan (2022-current)
University of Michigan (2022-current)
BS, Chemical Engineering, Boğaziçi University
BS, Chemical Engineering, Boğaziçi University
email: eceakin “@” umich.edu
email: eceakin “@” umich.edu
Research interests: directed evolution, machine learning, antibody multiobjective optimization, brain drug delivery, bispecific antibodies, nanobodies, VHHs
Research interests: directed evolution, machine learning, antibody multiobjective optimization, brain drug delivery, bispecific antibodies, nanobodies, VHHs
Chloe Brown
Chloe Brown
Doctoral Student (Chemical Engineering)
Doctoral Student (Chemical Engineering)
University of Michigan (2023-current)
University of Michigan (2023-current)
MChE, Chemical Engineering, Carnegie Mellon University
MChE, Chemical Engineering, Carnegie Mellon University
BS, Chemical Engineering, Carnegie Mellon University
BS, Chemical Engineering, Carnegie Mellon University
email: chloebr “@” umich.edu
email: chloebr “@” umich.edu
Research interests: protein computational design and analysis, protein language models, machine learning and artificial intelligence, antibody engineering and optimization
Research interests: protein computational design and analysis, protein language models, machine learning and artificial intelligence, antibody engineering and optimization
Yu-Hui (Eva) Huang
Yu-Hui (Eva) Huang
Doctoral Student (Chemical Engineering)
Doctoral Student (Chemical Engineering)
University of Michigan (2023-current)
University of Michigan (2023-current)
MS, Chemical Engineering, University of California, Berkeley
MS, Chemical Engineering, University of California, Berkeley
BS, Chemical Engineering, National Taiwan University
BS, Chemical Engineering, National Taiwan University
email: evahuang “@” umich.edu
email: evahuang “@” umich.edu
Research interests: antibody therapeutics, antibody engineering, developability analysis, high-throughput screening, machine learning
Research interests: antibody therapeutics, antibody engineering, developability analysis, high-throughput screening, machine learning
Dat Le Quoc Doi
Dat Le Quoc Doi
Doctoral Student (Chemical Engineering)
Doctoral Student (Chemical Engineering)
University of Michigan (2023-current)
University of Michigan (2023-current)
BS, Chemical Engineering, New Mexico State University
BS, Chemical Engineering, New Mexico State University
email: ddoi “@” umich.edu
email: ddoi “@” umich.edu
Research interests: bispecific antibodies, brain drug delivery, directed evolution, antibody engineering, machine learning
Research interests: bispecific antibodies, brain drug delivery, directed evolution, antibody engineering, machine learning
Juan Jiménez Mejía
Juan Jiménez Mejía
Doctoral Student (Chemical Engineering), co-advised with Dr. Thurber
Doctoral Student (Chemical Engineering), co-advised with Dr. Thurber
University of Michigan (2023-current)
University of Michigan (2023-current)
BS, Chemical Engineering, University of Florida
BS, Chemical Engineering, University of Florida
email: juanjim “@” umich.edu
email: juanjim “@” umich.edu
Research interests: brain drug delivery, antibody therapeutics, pharmacokinetic modeling, cancer
Research interests: brain drug delivery, antibody therapeutics, pharmacokinetic modeling, cancer