Lab members

Craig Streu

Visiting Professor (Albion College)

Ph.D., Chemistry, University of Pennsylvania

B.A., Chemistry, Albion College

email: cstreu “@” albion.edu

Research interests: Drug discovery, directed evolution, biomolecular engineering, monoclonal antibodies, chemical methods for studying and modifying biological systems

John Schardt

Postdoctoral Fellow

Ph.D., Bioengineering, University of Maryland, College Park

B.S., Bioengineering, Lehigh University

email: jschardt “@” med.umich.edu

Research interests: Agonist antibodies, antibody discovery and engineering, functional screening for antibody discovery

Wenjia Lou

Postdoctoral Fellow

Ph.D. Molecular Biology and Biotechnology, Wayne State University

M.S., Biochemistry and Molecular Biology, Zhejiang Sci-Tech University

B.S., Biological Sciences, Zhejiang University

email: wenjial “@” med.umich.edu

Research interests: Biomolecular engineering, directed evolution, protein engineering, drug-like antibody properties, next-generation sequencing, conformational antibodies

Alec Desai

Doctoral Student (Chemical Engineering)

University of Michigan (2015-current)

B.S., Chemical Engineering - Institute of Chemical Technology

email: aldesai “@” umich.edu

Research interests: Antibody design and engineering, conformational antibodies, directed evolution, Alzheimer’s disease, tau, amyloid

Magfur Alam

Doctoral Student (Chemical & Biological Engineering)

Rensselaer Polytechnic Institute (2015-current)

B.S., Chemical Engineering - University of South Florida

email: alamm “@” rpi.edu

Research interests: Monoclonal antibody stability and aggregation, high-throughput screening, drug-like antibodies, biophysical analysis

Priyanka Gupta

Doctoral Student (Biophysics and Biochemistry)

Rensselaer Polytechnic Institute (2015-current)

M.S., Biotechnology - Texas Tech

email: guptap4 “@” rpi.edu

Research interests: Antibody engineering and stability, high-throughput screening, biophysical analysis, bispecific antibodies

Yulei Zhang

Doctoral Student (Chemical Engineering)

University of Michigan (2017-current)

M.S., University of Michigan, Ann Arbor

B.S., Rutgers University & Beijing University of Chemical Technology

email: yuleizh “@” umich.edu

Research interests: Prediction of drug-like properties of antibodies, antibody library design, bioinformatics analysis of antibody evolution, antibody specificity and affinity

Harkamal (Hark) Jhajj

Doctoral Student (Biomedical Engineering)

University of Michigan (2017-current)

B.S., University of Michigan, Dearborn

email: hjhajj “@” umich.edu

Research interests: agonist antibodies, antibody discovery, functional screens for agonist antibody discovery, protein engineering

Ghasidit (Meu) Pornnoppadol

Doctoral Student (Pharmaceutical Sciences)

University of Michigan (2017-current)

M.S., Korea Advanced Institute of Science and Technology (KAIST), South Korea

B.E., Chulalongkorn University, Thailand

email: ghasidit “@” umich.edu

Research interests: antibody discovery, conformational antibodies, Alzheimer’s disease, tauopathies, therapeutics, physicochemical analysis of monoclonal antibodies

Lina Wu

Doctoral Student (Chemical Engineering)

NIH Cellular Biotechnology (T32) Fellowship (2019-2021)

University of Michigan (2018-current)

B.S., Chemical Engineering, Univ. of Massachusetts, Amherst

email: linawu “@” umich.edu

Research interests: Antibody therapeutics, drug-like properties of antibodies, biophysical and bioinformatics analysis of antibody physicochemical properties, protein stability and formulation

Matthew Smith

Doctoral Student (Chemical Engineering)

NSF Graduate Research Fellow (2019-2022)

University of Michigan (2018-current)

B.S., Chemical Engineering, Michigan State

email: mduncans “@” umich.edu

Research interests: antibody discovery, antibody library design, next-generation sequencing, computational antibody design, conformational antibodies, functional screens for antibody discovery

Jennifer Zupancic

Doctoral Student (Chemical Engineering)

University of Michigan (2018-current)

B.S., Bioengineering and Chemistry, University of Illinois, Urbana-Champaign

email: jenzup “@” umich.edu

Research interests: antibody discovery, conformational antibodies, Alzheimer’s disease, tauopathies, therapeutics, physicochemical analysis of monoclonal antibodies

Emily Makowski

Doctoral student (Pharmaceutical Sciences)

University of Michigan (2018-current)

B.S., Chemistry, The Ohio State University

email: emilymak “@” med.umich.edu

Research interests: antibody stability, protein engineering, bioinformatics, prediction of drug-like antibody properties

Manali Sawant

Doctoral Student (Pharmaceutical Sciences)

University of Michigan (2018-current)

B.S., Bioengineering and Materials Science, University of California, Berkeley

M.S., Chemical Engineering, University of Southern California

email: manalis “@” med.umich.edu

Research interests: antibody discovery, protein engineering, therapeutics, physicochemical analysis of monoclonal antibodies, prediction of drug-like antibody properties