Molecular Biotechnology @ Tessier lab
Our mission
The Tessier lab aims to develop best-in-class therapeutic antibodies and apply them to address multiple key biomedical challenges:
1. Bispecific antibodies for brain delivery of biologics, including antibodies (agonists and antagonists), cytokines, and gene silencing agents
2. Therapeutic brain drug delivery applications, including treating neurodegenerative (Alzheimer's and Parkinson's disease) and autoimmune (Multiple Sclerosis) disorders, brain cancer and acute disorders (Traumatic Brain Injury)
3. Conformational antibodies for detecting and treating neurodegenerative disorders
4. Non-invasive methods for modulating gene expression in the brain
5 Antibody-drug conjugates for treating cancer and gene silencing applications
6. Agonist and bispecific antibodies that activate T cells for treating cancer
To accomplish this, we develop next-generation technologies for designing, discovering, engineering, characterizing, formulating, and delivering therapeutic antibodies. Our technology development efforts are focused in three main areas:
1. Protein engineering and directed evolution
2. Biomolecular screening and high-throughput characterization
3. Machine learning, artificial intelligence, and computational predictions
Our logo embodies our work
The Tessier Lab logo is a visual representation of the lab’s pioneering work in therapeutic antibodies, with a particular focus on brain and central nervous system delivery. At the center of the design is a stylized brain, with its gyri and sulci seamlessly transformed into two key elements: an antibody structure and a computational network. This fusion symbolizes the lab’s dedication to antibody engineering and its integration of machine learning for advancing biomedical solutions.
Extending from the base of the brain is the spinal cord, which reflects the lab's emphasis on addressing central nervous system disorders. This spinal cord is intertwined into a double-stranded DNA helix, signifying modulation of gene expression. The DNA also serves as the blueprint from which antibodies are designed, symbolizing the core of the lab’s innovation.
The entire design reflects the Tessier Lab’s mission to develop cutting-edge, next-generation technologies in therapeutic antibodies, protein engineering, and computational predictions, all aimed at solving critical biomedical challenges. The logo’s minimalist yet meaningful design captures the essence of the lab’s focus on science, innovation, and the future of medicine.
(Designed and written by lab member Eva Huang)